Conhecimento teórico de graduandos sobre parada cardiorrespiratória no suporte básico de vida / Conocimientos teóricos de los estudiantes universitarios sobre la parada cardiorrespiratoria en soporte vital básico / Theoretical knowledge of undergraduates on cardiorespiratory arrest in basic life support

Objective identificar o conhecimento teórico de graduandos de cursos que não são da saúde sobre parada cardiorrespiratória no suporte básico de vida Method pesquisa descritiva e exploratória de natureza quantitativa realizada com graduandos de universidade pública localizada no Noroeste do Paraná, em 2019. Para coleta dos dados, utilizou-se questionário, contendo caracterização do sujeito e dez questões referentes ao reconhecimento e atendimento de situações de parada cardiorrespiratória e reanimação cardiopulmonar. Os dados foram tabulados e analisados. Results não se consideraram aptos para atendimento de evento de parada cardiorrespiratória 94,0% dos participantes; 92,6% não sabiam detectar essa condição; e 95,5% não souberam qual conduta adotar. Conclusion o conhecimento teórico de graduandos de cursos que não são da saúde sobre parada cardiorrespiratória foi insuficiente e é necessário treinamento para leigos em situações de emergência, para que o atendimento seja iniciado correta e imediatamente, sem postergar acionamento de serviço médico de emergência.

Objetivo identificar los conocimientos teóricos de los estudiantes universitarios de cursos no sanitarios sobre la parada cardiorrespiratoria en soporte vital básico. Método investigación descriptiva y exploratoria de carácter cuantitativo realizada con egresados de universidad pública ubicada en el Noroeste de Paraná, en 2019. Para la recolección de datos se utilizó un cuestionario, que contenía caracterización del sujeto y diez preguntas relacionadas con el reconocimiento y asistencia de situaciones de paro cardiorrespiratorio y reanimación cardiopulmonar. Los datos fueron tabulados y analizados. Resultados el 94,0% de los participantes no se consideraron aptos para el evento de paro cardiorrespiratorio; El 92,6% no sabía cómo detectar esta afección; y el 95,5% no sabía qué conducta adoptar. Conclusión los conocimientos teóricos de los estudiantes universitarios de cursos no sanitarios sobre parada cardiorrespiratoria fueron insuficientes y se requiere capacitación para los laicos en situaciones de emergencia, de modo que la atención se inicie de manera correcta e inmediata, sin posponer la activación del servicio médico de emergencia.

Objective to identify the theoretical knowledge of undergraduates of non-health courses about cardiorespiratory arrest on basic life support. Method descriptive and exploratory research of quantitative nature carried out with graduates of public university located in the Northwest of Paraná, in 2019. For data collection, a questionnaire was used, containing characterization of the subject and ten questions related to the recognition and attendance of situations of cardiorespiratory arrest and cardiopulmonary resuscitation. The data were tabulated and analyzed. Results 94.0% of the participants were not considered fit for cardiorespiratory arrest event; 92.6% did not know how to detect this condition; and 95.5% did not know which conduct to adopt. Conclusion the theoretical knowledge of undergraduates of non-health courses about cardiorespiratory arrest was insufficient and training is required for lay people in emergency situations, so that care is started correctly and immediately, without postponing emergency medical service activation.

Glandular Odontogenic Cyst in Dentigerous Relationship: An Uncommon Case Report.

Glandular odontogenic cyst (GOC) is an uncommon cyst of the jaw. Less than 200 cases are reported in the literature, and only 22 cases are associated with an unerupted tooth (dentigerous relationship). Although it is an asymptomatic lesion, it can be destructive and has high recurrence rates. The diagnosis can be especially challenging due to the lack of distinct diagnostic clinic-radiological criteria and nonspecific microscopic features, mimicking benign and malignant lesions. Conservative surgical treatment has been the choice for most surgeons, but marginal or partial jaw resection has been reported. This report describes a rare case of GOC in a dentigerous relationship, which was treated with enucleation and peripheral osteotomy.

Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report.

BACKGROUND: Granular cell tumor is a rare benign tumor that can present a pseudoepitheliomatous hyperplasia of the covering epithelium. This lesion is not encapsulated and can be characterized by a pseudo invasive growth pattern, represented by the tumoral cells that infiltrate between adjacent connective tissue elements. Diagnostic difficulties may arise because histopathological features of the pronounced pseudoepitheliomatous hyperplasia can be confused with a well-differentiated oral squamous cell carcinoma. The aim of this case report is to demonstrate the role of an immunohistochemical panel in the diagnosis of a granular cell tumor in the tongue with clinical and microscopic features resembling an oral squamous cell carcinoma. CASE PRESENTATION: A 44-year-old white man with a history of heavy smoking and alcohol abuse presented an ulcerated nodular lesion in the dorsum of the tongue. The lesion was asymptomatic with fast growth. The clinical diagnosis was an oral squamous cell carcinoma. An incisional biopsy was performed and the ensuing histopathological analysis showed a pseudoepitheliomatous hyperplasia in the overlying epithelium mimicking the invasion of epithelial tumor cells into the connective tissue as in an oral squamous cell carcinoma. Immunohistochemical antibodies (S-100, vimentin, CD68, p53, Ki-67, E-cadherin, collagen IV and cytokeratin AE1/AE3) were used to characterize molecular aspects of the lesion. Strong staining of S-100 protein, CD68, vimentin, E-cadherin and low proliferative activity observed with Ki-67 expression confirmed the diagnosis of a granular cell tumor. The patient was submitted to surgical excision of the whole lesion. At a 12-month check-up, there was no evidence of recurrence. CONCLUSION: This case report showed that the immunohistochemical profile was helpful in determining the clinical behavior of the tumor and establishing the final diagnosis with appropriate treatment.

Pleomorphic adenoma of oral minor salivary glands: An investigation of its neoplastic potential based on apoptosis, mucosecretory activity and cellular proliferation.

OBJECTIVE: The aim of this study was to investigate the neoplastic potential of the PA of minor oral salivary glands measured by apoptosis (Bcl-2, Bax and p53), mucosecretory activity (MUC1), and cellular proliferation (Ki-67). DESIGN: Thirty-one cases of PA of the oral cavity and four controls (C) taken from normal oral minor salivary glands were analyzed using the immunohistochemistry technique. The proteins were detected utilizing a semi-quantitative method (scores) as follows: (-) negative ≤5%, (+) low 6-25%, (++) moderate 26-50% and (+++) high >50% of positive tumour cells. The apoptotic indices were evaluated by the ratio Bcl-2/Bax. Non-parametric comparison and correlation tests were used for analysis. RESULTS: The data showed high staining of anti-apoptotic protein Bcl-2 in both groups (PA=57.9%; C=67.7%) and a significantly lower expression of pro-apoptotic protein Bax (PA=22.7%; C=97.7%) and MUC1 (PA=14%; C=82.3%) in PA than in C (p<0.001). On the other hand, a similar expression of Ki-67 and p53 proteins (≤5%) was seen in both PA and C. In PA, only 2/31 cases showed the ratio Bcl-2/Bax<1.There was no difference in cellular expression with regard to clinical variables or clinical outcome (p>0.05). CONCLUSION: The neoplastic potential of PA could be associated with an imbalance in apoptotic processes and a lower index of cellular proliferation. Mucosecretory activity does not play a significant role in primary PA.